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Use the informational power of your DNA to inform on genetic risk factors with head trauma. Keep your family SimplySafe™.

 

KEEP YOUR HEAD IN THE GAME.

The only full sequence genetic test that detects your ApoE variation.

 

 

PREVENT & PROTECT

 

Are you sure of the safety of yourself and your family partaking in sport activities? Don’t guess, know.

 

The damaging effects of brain injury and/or concussion from sports such as rugby, hockey and soccer are around 8 times more likely if the individual is a carrier of the ApoE ε4 gene (Wilhemus et al., 2005; Sun et al., 2008).

 

REASONS WHY YOU SHOULD CHOOSE TO BE SIMPLYSAFE™

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KNOW

Your genetic variations on ApoE.

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BETTER UNDERSTAND

Your risks of brain trauma after concussion

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HAVE CONFIDENCE

In the sports and activities you choose

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BETTER EQUIP YOUR FAMILY

During high impact sports

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MINIMISE STRESS

After a concussion concurs

Millions of people have two copies of the ApoE ε4 variation and are therefore categorized as high-risk individuals. Up to 15% of the population have at least one copy of ApoE ε4 (Nathoo et al., 2003; Smith et al., 2003).

WHAT DOES YOUR DNA SAY?

 

The ApoE ε4 gene has been linked with negative outcomes after traumatic brain injury or concussions.

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The ApoE gene is found on chromosome 19 and the variation is determined by resulting amino acids in positions 112 and 158.

ApoE encodes for apolipoprotein E, a protein that regulates the binding and distribution of cholesterol and triglycerides in the blood throughout your body.

ApoE has three variations:

ApoE ε2 = low risk
ApoE ε3 = neutral
ApoE ε4 = high risk

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SIMPLY PUT

Some variations of ApoE can become less efficient in clearing the build up of cholesterol, commonly referred to as plaque, from your blood after experiencing a concussion or head injury.

People with ε4 variations should avoid high impact sports, where the risk of head injury can significantly increase.

WHAT YOU GET

 

YOUR PERSONAL RESULTS WILL REVEAL:

Your genetic variation on ApoE

Results that last a lifetime

Knowledge of possible risk factors of brain trauma after a concussion

Safest sports and activities best suited for your variation

Resources for ApoE carriers

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IMPORTANT LIFE DECISIONS

SIMPLE ENOUGH! TEST NOW

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