Tests included in the Profile:
- Melatonin (MT6s x 4)
- Free Cortisol (C x 4)
A Simple, Convenient, At-Home Testing Option
- Circumvents the disadvantages of serum, saliva, and 24-hour urine tests commonly used for testing these hormones.
- Collecting four dried urine strips atfour time points during the day iseasy and convenient.
- First morning MT6s representsnight time melatonin production -no need to sample in the middle of the night.
- Cortisol and MT6s areexceptionally stable in dried urinefor weeks at room temperature,allowing flexibility in collection,shipment, testing, and storage.
- Results expressed in μg/gcreatinine take into account thehydration status of the patient, sothat test results are accurate evenwhen urine is very concentrated ordilute.
Adequate sleep has long been known to be vital to good health. Melatonin, a hormone produced by the pineal gland during the dark phase of the light/dark cycle, regulates the sleep/wake cycle and the “biological clock”. However, it is now known also to have free radical scavenging and antioxidant properties and a significant role in stimulating the immune system to protect against the growth of abnormal tissues such as breast and prostate cancers. Melatonin is also neuroprotective. Adequate melatonin production during the night, as well as suppression of production during the day by exposure to daylight, form a balance that is vital to optimal health. Circulating melatonin is rapidly and efficiently hydroxylated and conjugated with sulfate in the liver to form its primary metabolite, 6-sulfatoxymelatonin (MT6s), and excreted into urine; it is this metabolite that is measured in the Sleep Balance Profile.