Appropriate iodine levels support optimum thyroid function
essential for performance, protect against hypothyroidism,
and provide antimicrobial protection in body tissues.





Iodine’s effectiveness as an antimicrobial has been known for over a hundred years as it has been used for preoperative surgical skin preparation to prevent infection. As an antimicrobial, it is of relevance that iodine from the bloodstream concentrates in a broad spectrum of tissues that are repeatedly exposed to infectious organisms (e.g., skin, eyes, gastrointestinal tract, salivary gland, nasal and oral mucosa, breast ducts, uterine lining, prostate).

Uptake of iodide by these tissues and enzymatic formation of reactive iodine compounds (e.g., hypoiodous acid) would serve the role of a protective antimicrobial, working in concert with the immune system. It is also of interest that like the thyroid, many of these iodine-concentrating tissues (e.g., skin, eyes, gastrointestinal tract) are the most sensitive to the adverse effects of iodine excess.


An easy-to-do home collection dried-urine test for:

Iodine and Creatinine

Collecting and Testing Urinary Iodine

Iodine is collected twice during the day (first morning and last night void) on filter strips either by dipping the strip in urine collected in a cup, or by urinating directly on the strip. The urine-saturated filter strips are allowed to dry overnight and then sent to the laboratory for iodine and creatinine testing. The iodine content of the dried filter strips is determined following extraction and measurement by inductively coupled plasma mass spectrometry (ICP-MS). Creatinine is measured in the same urine extract by a modification of the Jaffe method. Iodine is measured in μg per liter of urine and the average of morning and night levels is taken. The creatinine level is used to correct for hydration status of the individual, because it is dependent on urine dilution. Results are therefore expressed in μg of iodine per g of creatinine.